Diagnosis and Change in Diagnosis

Diagnosis and Change in Diagnosis - Variable Definition Table:

Field Name

Description

Values

diagnosis The diagnosis is an opportunity for the site investigator to give their opinion on a participant's most likely clinical diagnosis, regardless of cohort. The diagnosis may change over time because the site investigator may update the diagnosis at every longitudinal visit based on their opinion.

No PD Nor Other

Idiopathic PD

Parkinson's Disease

Prodromal non-motor

PD

Prodromal motor PD

No PD no Other

Multiple System Atrophy

Essential Tremor Progressive

Other Neurological

Parkinsonism

Demential with Lewy

Corticobasal

initial_diagnosis Initial diagnosis  
most_recent_diagnosis Most recent diagnosis  
change_in_diagnosis Change in diagnosis indicator Yes
No
Null
change_in_diagnosis_date Change in diagnosis date YYYY-MM format
date_of_pd_diagnosis Date of Parkinson's disease diagnosis YYYY-MM format
age_at_diagnosis Age at Parkinson's disease diagnosis ###

 

Tables that Reference this Variable:

  • PD Medical History
     

Data Type Information:

Field Name

Type

Mode

diagnosis STRING NULLABLE
initial_diagnosis STRING NULLABLE
most_recent_diagnosis STRING NULLABLE
change_in_diagnosis STRING NULLABLE
change_in_diagnosis_date STRING NULLABLE
date_of_pd_diagnosis STRING NULLABLE
age_at_diagnosis INTEGER NULLABLE


Curation Notations:

  1. Appropriate Diagnosis (APPRDX) in PPMI and BioFIND were used as Study Arm and Most Likely Primary Diagnosis (PRIMDIAG) was used as Diagnosis. In PDBP Case/Control were used to identify three Study Arm values.
  2. Diagnosis in PDBP were cleaned and standardized as suggested by CDH group.
  3. Blank diagnosis values were filled with the value from the previous visit based on the participant_id. When a change in diagnosis occurs between visits (PDBP), the new diagnosis was associated with whichever visit is closest to the change date. The closest visit may be before the date of change logged in the system. These updates were completed manually.