News & Updates

Next Generation Sequencing in Post Mortem Tissue from Patients with Parkinson’s Disease

By:
Debra Babcock, PhD, MD

 


Funding Opportunity Announcement (FOA) Number: 

RFA-NS-21-017

Full Funding Opportunity Source: 

https://grants.nih.gov/grants/guide/rfa-files/RFA-NS-21-017.html

Funding Opportunity Purpose:

 This FOA seeks applications to perform single nucleus RNA sequencing (snRNA seq) and whole genome sequencing (WGS) in post-mortem brain tissue from 100 patients with Parkinson's Disease (PD) and normal controls. Applicants will be expected to have access to high quality brain tissue and perform sequencing in four separate brain regions, including some regions known to be affected by PD pathology and at least one region known to be relatively unaffected. All sequencing data and any available pre-mortem clinical data will be broadly shared with the research community through the Accelerating Medicine Partnership in Parkinson's Disease (AMP PD) Knowledge Portal.

Key Dates

Date Date Activity/Milestone
January 6, 2020 Posted Date
February 15, 2021 Open Date (Earliest Submission Date)
March 15, 2021 Application Due Date(s)
July, 2021 Scientific Merit Review
October, 2021 Advisory Council Review
October, 2021 Earliest Start Date
March 16, 2021 Expiration Date

Primary Application Submission Contact

Debra Babcock, PhD, MD
National Institute of Neurological Disorders and Stroke (NINDS)
Telephone: 301-496-9964 
Email: dbabcock@mail.nih.gov